Observations on the Relation between Ionized and Total Calcium in Normal and Abnormal Sera and Their Ultrafiltrates
نویسندگان
چکیده
The frog’s heart has been found to be a sensitive indicator of the concentration of calcium ions in protein-containing fluids (1). Using the values derived by this method, McLean and Hastings (2) have shown that the total calcium, calcium ions, (Gaff), and total protein of blood serum bear a relationship to one another which apparently follows the law of mass action. Assuming that each molecule of protein acts as a divalent ion towards calcium, and employing the factor 0.243 for base-combining capacity of protein (3), they find that the equation
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